Colt was the originator of that sized 1911. They got it right the first time, too. I've owned a Kimber UC and it was a lemon, although other have had different experiences. Doubtful, however, you will find a negative comment about the Colt Defender. They are fantastic shooter with managable recoil for the size, as well as surprisingly good accuracy for such a short barrel.
If recoil of a .45 is a possible issue for your wife (it is for mine), I would recommend a Springfield EMP9. That's on my short list.
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