I'll speak from experience

. I own three, cowhide backing. 9mm Gl**k, OWB 1911 and IWB 1911. While I am absolutely sure the 1911 one will be replaced by the beautiful work that Lane is doing for me, I can assure you this:
If you think it comfortable now, wait until the leather molds to your body. It will take about a month of daily wear, your body heat and sweat wll do the molding. My Crossbreed now fits in exactly one place at 3:30 oclock position. This is the first IWB holster I've ever had that I literally do not feel throughout the day.I forget I'm wearing it. My new DW CCO needs leather though... and Lane is "da Man!" for leather work. I'll allow my Sig or the SA to wear the kydex going forward.
On the kydex note. I HAVE allowed the DW in the crossbreed, and there is no visible wear on the firearm. Keep the kydex clean, the gun oiled, and you should have no problems. I also found that wearing a pair of Perry suspenders that hook to your belt (no metal clips) help to keep the gunside of your pants at the proper position.
Good luck with your new holster!
One Well Used and very comfortable Crossbreed. The dye is NOT wearing off, its just the way the flash caught the marks in the leather. It's still one solid color.